Biophysics Model Development Describing 3D Energy-Tissue Interaction for Thermal Ablation Treatments in Cancer Care


The project is supervised by Philips Research Eindhoven and Prof. Karen Veroy-Grepl. The focus of the project is to enable fast and accurate forward modeling of radio-frequency ablation procedures in liver cancer care. The key research objectives are as follows:

  1. i) Development of numerical models for coupled biophysics problems, able to predict the temperature distribution in tissue, as a result of energy distribution from different treatment modality probes / devices (HIFU, microwave, laser, RF)
  2. ii) Development of multiscale modeling approaches to describe blood flow heat sinking effects

iii) Optimizing numerical solvers enabling fast computation times

  1. iv) Validation of models against available test results