Dr. Jeyashree Krishnan

Dr. Jeyashree Krishnan


Funding: JRC/Bayer

Advisor / Co. Advisor

Prof. Schuppert / Dr. Di Napoli

Thesis Title

Simulations of Complex Biological Networks


Modeling and Simulation of Complex Networks in Systems Biology

This page may not be well-updated. Please visit my JRC-Combine page.


03/2015- 12/2019 PhD, Aachen Institute for advanced study in Computational Engineering Science (AICES) and Joint Research Center for Computational Biomedicine (JRC-Combine), RWTH Aachen University, Germany.
10/2012-10/2014 Master of Science in Simulation Sciences, German Research School for Simulation Sciences (GRS), RWTH Aachen University, Germany.
09/2008-05/2012 Bachelor of Technology in Biotechnology, Anna University, India.


Research Interests

Network Analysis, Data Analysis, Systems Biology


Professional Career

03/2019- 05/2019 Research visit, McGill University, Canada
10/2016-12/2019 Researcher, Joint Research Center for Computational Biomedicine (JRC-Combine), RWTH Aachen University, Aachen, Germany
03/2015- 10/2016 Researcher, Institute of Neuroscience and Medicine (INM)-6 and Institute for Advanced Simulation (IAS)-6, Forschungszentrum Jülich, Germany. 
04/2014-10/2014 Masters thesis student, Institute of Neuroscience and Medicine (INM)-6, Forschungszentrum Jülich, Germany. 
09/2013-10/2013 Student Assistant, Aachen Institute for advanced study in Computational Engineering Science (AICES), RWTH Aachen University, Aachen, Germany.
07/2013- 08/2013 Student Assistant, German Research School for Simulation Sciences (GRS) , RWTH Aachen University, Aachen, Germany.
11/2011-05/2012 Bachelors thesis student, Department of Chemical Engineering, Indian Institute of Technology Bombay, India.
04/2010-06/2010 Student Intern, Jawaharlal Nehru Medical College & Hospital, Ajmer, India.


A Long-Range Ising Model of Barabási-Albert Network,  Krishnan J, Torabi R, Honerkamp C, Di Napoli E, Schuppert A,  arxiv:2005.05045 

A Modified Ising Model of Barabási-Albert Network with Gene-type Spins,   Krishnan J, Torabi R, Schuppert A, Di Napoli E, . Journal of Mathematical Biology, 81(3), 769-798(2020) doi: 10.1007/s00285-020-01518-6

Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine content in ventral midbrain cells derived from human skin,   M. Jefri, S. Bell, H. Peng, G. Maussion, V. Soubannier, H. Wu, H. Silveira, J.-F. Theroux, J. Krishnan, L.-A. O’Leary, X. Zhang, Y. Zhang, L. Moquin, A. Gratton, A. Schuppert, T.-M. Durcan, E.-A. Fon, C. Ernst, submitted to Stem Cells Translational Medicine, under review. 

Metastable Regimes and Tipping Points of Biochemical Networks with Potential Applications in Precision Medicine,   Samal S.S., Krishnan J., Esfahani A.H., Lüders C., Weber A., Radulescu O. (2019)  In: Liò P., Zuliani P. (eds) Automated Reasoning for Systems Biology and Medicine. Computational Biology, vol 30. Springer, Cham

NEST 2.16.0,  Charl Linssen, Mikkel Elle Lepperød, Jessica Mitchell, Jari Pronold, Jochen Martin Eppler, Chrisitan Keup, Alexander Peyser, Susanne Kunkel, Philipp Weidel, Yannick Nodem, Dennis Terhorst, Rajalekshmi Deepu, Moritz Deger, Jan Hahne, Ankur Sinha, Alberto Antonietti, Maximilian Schmidt, Luciano Paz, Jesús Garrido, Tammo Ippen, Luis Riquelme, Alex Serenko, Tobias Kühn, Itaru Kitayama, Håkon Mørk, Sebastian Spreizer, Jakob Jordan, Jeyashree Krishnan, Mario Senden, Espen Hagen, Alexey Shusharin, Stine Brekke Vennemo, Dimitri Rodarie, Abigail Morrison, Steffen Graber, Jannis Schuecker, Sandra Diaz, Barna Zajzon, and Hans Ekkehard Plesser   (2018). doi:10.5281/zenodo.1400175.

Perfect detection of spikes in the Linear Sub-threshold Dynamics of Point Neurons,  Krishnan J, Porta Mana P, Helias M, Diesmann M and Di Napoli E (2018), Front. Neuroinform. 11:75. doi: 10.3389/fninf.2017.00075

Extracts of Ocimum on Imipenem Resistant Gram Negative Bacteria, V. Rastogi, C. Vijay, J. Krishnan, P. S. Nirwan, J. Microbio. & Parasitology, 2015. 

Conference Presentations


Conference on Complex Systems 2019 (CCS'19)
Singapore,  1-4 October 2019

SIAM Computational Science and Engineering (SIAM CSE'19)
Washington, USA, 25-28 February 2019.

Mediterranean School on Complex Networks
Salina, Italy, 1-8 September 2018.

Conference on Mathematics of Multiscale Biology
Nottingham, UK, 2-6 July 2018.

Systems Biology of Human Diseases 2018
LA, USA, 4-6 June 2018.

Programming a D-Wave Quantum Computer
Juelich, Germany, 19-20 March 2018.

Conference on Complex Systems 2017
Cancun, Mexico, 17-22 September 2017.

AC.CES 2017
Aachen, Germany, 27-28 July 2017.

SIAM Conference 2017
Pittsburgh, USA, 10-14 July 2017.

International Conference on Systems Biology of Human Disease
Heidelberg, Germany, 5-7 July 2017.

Summer School on Statistical Physics of Complex Systems
Palma de Mallorca, Spain, 19-30 June 2017.

IAS Symposium
Jülich, Germany, 5-6 December 2016.

Bernstein Conference 
Berlin, Germany, 12-16 September 2016.

Supercomputing and Modeling for the Human Brain (SMHB) General Assembly
Jülich, Germany, 20 - 21 April 2016.

Workshop on Future Computing
Manchester, UK, 11 - 15 January 2016.

2nd HBP School
Obergurgl, Austria, 3-9 August 2015.

3rd Aachen Conference on Computational Engineering Science (AC.CES)
Aachen, Germany, 23-24 July 2015.

World Congress on Biotechnology
Hyderabad, India, 21-23 March 2011.

Stem Cell and Regenerative Medicine Conference
Sri Ramachandra University, India, April 2010.



NeuroNode Meeting
Guildford, UK, 14-15 May 2019

SIAM Artificial Intelligence Seminar Series
SIAM Student Chapter, Aachen, Germany, 21st September 2015.

Parallel Programming in Computational Engineering Science (PPCES)
Aachen, Germany, 16-20 March 2015.

Jülich Guest Student Programme
(accepted) Jülich, Germany, August 2013.

Scientific Python Workshop
Jülich, Germany, 18-20 March 2013.

Winter Course in Mathematical Modeling and Computational Sciences
AU-KBC, India, May 2010.

Summer Training course on C​ancer Imaging Methods
Cancer Institute, India, January 2010.


Modeling and Simulation of Complex Networks in Systems Biology [PDF]
PhD Thesis, RWTH Aachen University, Germany, 2019.

Detection of Threshold Crossings in the Leaky Integrate-and-Fire Neuron Model with Alpha-Shaped Post-synaptic Currents in Time-Driven Simulations [PDF]
Master Thesis, RWTH Aachen University, Germany, 2014.



Email: krishnan (AT) aices (DOT) rwth-aachen (DOT) de

          (or)  jkrishnan (AT) ukaachen (DOT) de