Maryam Montazeri M.Sc.

Maryam Montazeri M.Sc.

Member

Bayer

Advisor / Co. Advisor

Prof. Schuppert

Thesis Title

Modelling of Disease Progression in Myeloproliferative Neoplasm, a System Medicine Approach

Contact


Joint Research Center for Computational Biomedicine

RWTH Aachen University
Campus Boulevard 79, Level 4

52074 Aachen

Phone: + 49 (0) 241 8099201
Email: montazeri@aices.rwth-aachen.de

Education

03/2014 - present Doctoral student at AICES Graduate School, RWTH Aachen University, Germany
10/2011 - 10/2013 M.Sc. in Biomedical Engineering, RWTH Aachen
09/2006 - 09/2010 B.Sc in Electrical Engineering (Electronics), University of Isfahan (Iran)

Research Interests

Data-driven disease Modelling. Mechanistic Modeling. Life Science.

Professional Career

10/2013-03/2014 Student Assistant, AICES Graduate School , RWTH Aachen.

Thesis

Thesis Title: Modeling disease Progression in Myeloproliferative Neoplasm, a System Medicine Approach

Project Outline

Complex diseases such as cancer can show markedly distinct phases that differ in their biological characterization and , crucially, in our ability to treat them. But what drives disease progression? How to different stages of disease differ? And how can we determine the stage of disease in a particular patient?In my work, I address these questions bu coupling mechanistic models of cancer progression in Myeloproliferative neoplasms with patient data, aiming for a better understanding of phases transitions in complex diseases that will inform and improve diagnosis and therapy.

Conferences

Cellular Heterogeneity EMBO 2015, Heidelberg (Poster Presentation)

SBMC 2016, 6th Conference on Systems Biology of Mamaalian cells, Munich (Poster Presentation)

Publication

Brehme M, Koschmieder S, Montazeri M, Copland M, Oehler VG, Radich JP,

Brümmendorf TH, Schuppert A , “Combined Population Dynamics and Entropy

Modelling Supports Patient Stratification in Chronic Myeloid Leukemia”, Sci Rep.

2016 Apr 6;6:24057